This up-to-date, comprehensive reference/text covers all aspects of gene therapy, including basic principles, viral and nonviral delivery systems, targeted diseases, regulatory issues, and FDA requirements.

Investigates genetic bullets to block HIV-1 replication and genetic guns to deliver antiviral agents! Including over 4000 references, drawings, micrographs, tables, and equations, and contributions from nearly 80 international experts, Gene Therapy examines:

donor cells, vector systems, and functional genes \n defines extra- and intracellular pathways and barriers for gene delivery \n details the advantages of myoblasts and RetroTet vectors \n addresses the interaction of micelles and liposomes with nucleic acids \n \tdescribes the formulations, pharmacology, and toxicology of oligonucleotides \n considers RNA catalysis and decoy RNAs \n \toutlines hematopoietic stem cell procurement \n reveals strategies to circumvent barriers to airway gene transfer \n discusses the bystander effect
\tand much more! \n
Offering perspective on how to choose the most responsive pathologies, Gene Therapy is a cutting-edge reference for biochemists, geneticists, hematologists, oncologists, molecular and cell biologists, virologists, and immunologists, and an excellent text for medical school and graduate students in these disciplines.

Product Info
Author :	Templeton, Nancy Smyth|Lasic, Danilo D.|Lasic, D. D.
ISBN :	9780824776657
Year of Publication:	36692